High throughput is the key word for modern
HPLC analysis. The SIL-HT is the best performing autosampler
in terms of sample injection speed, sample capacity, and minimizing
sample carryover of highly adsorbent sample components. These
features are in increasingly high demand and essential for
high throughput analysis. The SIL-HT has been developed to
meet such users' requirements and will also provide optimum
results in your lab. The SIL-HT is available in two versions:
the SIL-HTA, ambient model; and the SIL-HTC with sample temperature
control from 4 to 40C.
The SIL-HT maximizes analysis throughput with fast sample
injection and high sample capacity. Injection speed is 15
seconds for injecting samples of 10µL . The SIL-HT is
the fastest autosampler currently on the market.
Near-zero sample carryover
Recently, an increasing number of extremely basic and hydrophobic
components are being used in new drug formulations. Since
these chemical compounds strongly adsorb to the sampling needles
or rotor seals (mainly Vespel) of autosamplers, cross contamination
may not be reduced by simple rinsing. To minimize adsorption
of such compounds, the outer surface of the sampling needle
of the SIL-HT's autosampler is coated using a special, innovative
surface processing technology (patent pending). Furthermore,
by employing newly developed rotor seals and needle seals
made of PEEK, the SIL-HT dramatically reduces contamination,
even with the most highly adsorbent sample compounds. As a
result, the SIL-HT demonstrates nearly zero sample carryover.
The SIL-HT uses a needle-in-the-flow-path injection design
(also called direct injection method or total volume injection
method) and a high-performance measuring pump (6nL step resolution)
for enhanced accuracy. This results in superior repeatability
over conventional autosamplers. In addition, precious samples
are not wasted since the total volume aspirated is injected.