{"id":3279,"date":"2023-07-12T14:31:58","date_gmt":"2023-07-12T07:31:58","guid":{"rendered":"http:\/\/www.barascientific.com\/product\/?p=3279"},"modified":"2025-07-11T14:07:45","modified_gmt":"2025-07-11T07:07:45","slug":"nexera-lite-inert-high-performance-liquid-chromatograph","status":"publish","type":"post","link":"https:\/\/www.barascientific.com\/product\/nexera-lite-inert-high-performance-liquid-chromatograph\/","title":{"rendered":"Nexera lite inert &#8212; High Performance Liquid Chromatograph"},"content":{"rendered":"\n<p>Nexera lite inert is a robust HPLC system that eliminates the risk of corrosion by high-salt&nbsp;mobile phases and sample adsorption onto metal surfaces. It improves the data quality of protein analysis&nbsp;in biological samples with superior reproducibility, without any special considerations for stable and&nbsp;long-term use.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Improved Data Reliability by Preventing System Corrosion by Halogenic Salt<\/h2>\n\n\n\n<p>Aggregates of antibody drugs show immunogenicity and cause a decrease in purification efficiency and production. Therefore, an aggregation test is one of the most critical evaluations when manufacturing biopharmaceuticals and&nbsp;controlling their quality. However, a metal-free LC system is required for good repeatability over a long time due to&nbsp;high-concentration, salt-containing mobile phases such as Sodium chloride. With no metal material in the flow path, Nexera&nbsp;lite inert provides stable aggregate assay results with good repeatability.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><\/li><li>&nbsp;<\/li><li>Monoclonal IgG antibody aggregate analysis by size exclusion chromatographyte<\/li><li>Corrosion resistance test results of pump heads<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Superior Retention Time Stability by Highly Accurate Solvent Delivery<\/h2>\n\n\n\n<p>Thanks to the outstanding flow-rate stability, the Nexera lite inert provides excellent retention time repeatability.<\/p>\n\n\n\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/www.shimadzu.com\/an\/sites\/shimadzu.com.an\/files\/d7\/ckeditor\/an\/hplc\/nexera_lite_inert\/analysis_of_the_aggregates.jpg\" alt=\"Analysis of the aggregates in the antibody drug \"\/><\/figure>\n\n\n\n<p>Analysis of the aggregates in the antibody drug (n=5)<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Real-Time Monitoring of Mobile Phase pH<\/h2>\n\n\n\n<p>In ion exchange or size exclusion chromatography, the pH of the mobile phase sometimes affects&nbsp;the separation of compounds. The pH Monitor, pHM-40, continuously monitors and records the&nbsp;pH of the mobile phase. The pH and detector chromatograms are saved within the same data file and can be overlapped, ensuring efficient data traceability.<\/p>\n\n\n\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/www.shimadzu.com\/an\/sites\/shimadzu.com.an\/files\/d7\/ckeditor\/an\/hplc\/nexera_lite_inert\/system_configuration.jpg\" alt=\"System Configuration\"\/><\/figure>\n\n\n\n<p> <strong>\r\n<!--change the width and height value as you want.--> \r\n<!-- Do change \"index.htm\" to your real html name of the flippingbook--> \r\n<iframe  style=\"width:100%;height:450px\"  src=\"https:\/\/www.barascientific.com\/product\/wp-content\/uploads\/flipbook\/289\/book.html\"  seamless=\"seamless\" scrolling=\"no\" frameborder=\"0\" allowtransparency=\"true\" allowfullscreen mozallowfullscreen  webkitallowfullscreen ><\/iframe>\r\n<\/strong> <\/p>\n","protected":false},"excerpt":{"rendered":"<p>Nexera lite inert is a robust HPLC system that eliminates the risk of corrosion by high-salt&nbsp;mobile phases and sample adsorption onto metal surfaces. It improves the data quality of protein analysis&nbsp;in biological samples with superior reproducibility, without any special considerations for stable and&nbsp;long-term use. Improved Data Reliability by Preventing System Corrosion by Halogenic Salt Aggregates [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":3275,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[135],"tags":[],"class_list":{"0":"post-3279","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-high-performance-liquid-chromatograph"},"_links":{"self":[{"href":"https:\/\/www.barascientific.com\/product\/wp-json\/wp\/v2\/posts\/3279","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.barascientific.com\/product\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.barascientific.com\/product\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.barascientific.com\/product\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.barascientific.com\/product\/wp-json\/wp\/v2\/comments?post=3279"}],"version-history":[{"count":1,"href":"https:\/\/www.barascientific.com\/product\/wp-json\/wp\/v2\/posts\/3279\/revisions"}],"predecessor-version":[{"id":4602,"href":"https:\/\/www.barascientific.com\/product\/wp-json\/wp\/v2\/posts\/3279\/revisions\/4602"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.barascientific.com\/product\/wp-json\/wp\/v2\/media\/3275"}],"wp:attachment":[{"href":"https:\/\/www.barascientific.com\/product\/wp-json\/wp\/v2\/media?parent=3279"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.barascientific.com\/product\/wp-json\/wp\/v2\/categories?post=3279"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.barascientific.com\/product\/wp-json\/wp\/v2\/tags?post=3279"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}