The demands placed on analysis fueled by the
need to analyze compounds such as non-volatile and thermally
unstable compounds, and to perform trace analysis and ultra
high-sensitivity analysis on complex matrices have created a
a need for a new, more powerful HPLC detector. The focus of
efforts to develop such a detector has been to raise the selectivity
of target compounds to enable acquisition of reliable and definitive
qualitative data, while still relying on chromatography at the
initial separation stage.